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Old 1st September 2008, 06:22 PM
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Thumbs up seven doubleblind placebo controlled studies

Galphimia glauca (homeopathic remedy)

Seven double-blind, placebo-controlled studies involving a total of 752 participants have evaluated the potential benefits of Galphimia in relieving symptoms of hay fever. Potencies of the remedy used in these trials ranged from 2c to 3c. All of the studies evaluated improvements in allergic symptoms related to the eye, and some also considered symptoms related to the nose. Overall, the results were encouraging.


In the best of these studies, researchers evaluated the effectiveness of Galphimia glauca in alleviating hay fever symptoms in 201 people.10

The treatment group received Galphimia glauca 2c in a liquid solution of 43% alcohol, and the placebo was in an identical solution. Improvement was noted after 2 weeks, and the relative benefit of treatment over placebo continued to increase throughout the 4-week study period.
Not all of the studies found evidence of benefit. However, when researchers put the results of all the studies together, using sophisticated statistical methods called a meta-analysis, the results indicated that the remedy worked significantly better than the placebo in relieving the symptoms.

The success rate in those treated was an average of 78%, a rate that was superior to placebo by about a factor of 1.35.
Combining studies in this way is common in medical research. It is considered especially appropriate when the individual studies were quite similar, as they were in this case. However, there are many potential statistical pitfalls in a meta-analysis. One of the problems here is that not all of the double-blind studies produced statistically significant results on their own. Essentially, by doing a meta-analysis, researchers combined inconclusive trials to produce a conclusive result. While this is permissible, it is not entirely trustworthy.
Another problem is that all the studies were reported by one group of scientists. To confirm these results, we really need a study by an independent research team.
A subsequent double-blind study, enrolling almost 150 people, evaluated the effectiveness of a nasal spray containing homeopathic Galphimia glauca along with Luffa operculata, Histamine, and Sulphur by comparing it to a standard treatment for hay fever: cromolyn sodium.12 The results showed equal benefits.
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