I am 35 and have Polycystic Kidney Disease, at this point I am mostly asymptomatic aside from the occasional dull pains. I do have cysts that have grown in size. I am looking for any recommendations in homeopathic medicine that might be able to keep me i pretty good shape. Is there anything that can shrink cysts? Any information or suggestions would be appreciated.

Thank you,
Malikha

look for a good homeopathgood luck




rachel schreiber RCHom
classical homeopathy
tel/fax 972-2-6428550
mobile 972-50-8433223

The Center for Complementary Medicine
Shaare Zedek Medical Center - Jerusalem




> To: homeopathy (AT) homeolist (DOT) com
> From: homeolist (AT) otherhealth (DOT) com
> Date: Sun, 16 Aug 2009 04:16:41 +0100
> Subject: [H] PKD Polycystic Kidney Disease
>
>
> I am 35 and have Polycystic Kidney Disease, at this point I am mostly
> asymptomatic aside from the occasional dull pains. I do have cysts that
> have grown in size. I am looking for any recommendations in homeopathic
> medicine that might be able to keep me i pretty good shape. Is there
> anything that can shrink cysts? Any information or suggestions would be
> appreciated.
>
> Thank you,
> Malikha
>
>
> --
> malikha
> ------------------------------------------------------------------------
> malikha's Profile: http://www.otherhealth.com/members/malikha.html
> View this thread: PKD Polycystic Kidney Disease
>
>

Triptolide is a traditional Chinese medicine-derived inhibitor of
polycystic kidney disease.

SJ Leuenroth<http://www.camresearch.net/showcitationlist.php?surname=Leuenroth&initials=SJ >,
D Okuhara<http://www.camresearch.net/showcitationlist.php?surname=Okuhara&initials=D>,
JD Shotwell<http://www.camresearch.net/showcitationlist.php?surname=Shotwell&initials=JD> ,
GS Markowitz<http://www.camresearch.net/showcitationlist.php?surname=Markowitz&initials=GS >,
Z Yu <http://www.camresearch.net/showcitationlist.php?surname=Yu&initials=Z>,
S Somlo<http://www.camresearch.net/showcitationlist.php?surname=Somlo&initials=S>,
CM Crews<http://www.camresearch.net/showcitationlist.php?surname=Crews&initials=CM>
*Departments of *Molecular, Cellular, and Developmental Biology, Internal
Medicine, Genetics, Pharmacology, and Chemistry, Yale University, New Haven,
CT 06511.*

During kidney organogenesis, tubular epithelial cells proliferate until a
functional tubule is formed as sensed by cilia bending in response to fluid
flow. This flow-induced ciliary mechanosensation opens the calcium (Ca(2+))
channel polycystin-2 (PC2), resulting in a calcium flux-mediated cell cycle
arrest. Loss or mutation of either PC2 or its regulatory protein
polycystin-1 (PC1) results in autosomal dominant polycystic kidney disease
(ADPKD), characterized by cyst formation and growth and often leading to
renal failure and death. Here we show that triptolide, the active diterpene
in the traditional Chinese medicine Lei Gong Teng, induces Ca(2+) release by
a PC2-dependent mechanism. Furthermore, in a murine model of ADPKD,
triptolide arrests cellular proliferation and attenuates overall cyst
formation by restoring Ca(2+) signaling in these cells. We anticipate that
small molecule induction of PC2-dependent calcium release is likely to be a
valid therapeutic strategy for ADPKD.
[Pubmed Record - new
window]<http://www.ionchannels.org/redirect.php?linkurl=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=RetrieveAMPERSANDdb=pubmedAMPERSAND dopt=AbstractAMPERSANDlist_uids=17360534AMPERSANDq uery_hl=2&readtype=medline&site=camresearch&pmid=1 7360534&doctype=abstract>

On Wed, Aug 19, 2009 at 7:33 AM, rachel schreiber <rachelsr (AT) hotmail (DOT) com>wrote:

>
> look for a good homeopathgood luck
>
>
>
>
> rachel schreiber RCHom
> classical homeopathy
> tel/fax 972-2-6428550
> mobile 972-50-8433223
>
> The Center for Complementary Medicine
> Shaare Zedek Medical Center - Jerusalem
>
>
>
>
> > To: homeopathy (AT) homeolist (DOT) com
> > From: homeolist (AT) otherhealth (DOT) com
> > Date: Sun, 16 Aug 2009 04:16:41 +0100
> > Subject: [H] PKD Polycystic Kidney Disease
> >
> >
> > I am 35 and have Polycystic Kidney Disease, at this point I am mostly
> > asymptomatic aside from the occasional dull pains. I do have cysts that
> > have grown in size. I am looking for any recommendations in homeopathic
> > medicine that might be able to keep me i pretty good shape. Is there
> > anything that can shrink cysts? Any information or suggestions would be
> > appreciated.
> >
> > Thank you,
> > Malikha
> >
> >
> > --
> > malikha
> > ------------------------------------------------------------------------
> > malikha's Profile: http://www.otherhealth.com/members/malikha.html
> > View this thread: PKD Polycystic Kidney Disease
> >
> >

Does anyone have any information on apis 3x for the reduction of cysts?

Hi, my approach would be a constitutional remedy.
Cheers
Chris

homeolist (AT) otherhealth (DOT) com wrote:
> Does anyone have any information on apis 3x for the reduction of cysts?
>
>
>

Chris,
Are you a homeopath? How do I go about finding out me constitutional type? And would a constitutional approach help being as though my pkd is genetic?

Malikha

Over the years i have used the following formula [with some slight
variations sometimes] for ovarian cysts [of sizes which were "suspicious"]
I took the formula [combined the remedies] from Dr.med Emil Rehm: Bewahrte
homoopatische Rezepte [german]
Th results were very encouraging and as far as i remember in all cases, even
in one case of a teratoma which totally disappeared.
I did always also give at the same time: evening primrose oil,some 1 gram
per day.

On Wed, Aug 19, 2009 at 7:39 AM, harold jitschak bueno de mesquita <
bdmesq (AT) gmail (DOT) com> wrote:

>
> Triptolide is a traditional Chinese medicine-derived inhibitor of
> polycystic kidney disease.
>
> SJ Leuenroth<http://www.camresearch.net/showcitationlist.php?surname=Leuenroth&initials=SJ >,
> D Okuhara<http://www.camresearch.net/showcitationlist.php?surname=Okuhara&initials=D>,
> JD Shotwell<http://www.camresearch.net/showcitationlist.php?surname=Shotwell&initials=JD> ,
> GS Markowitz<http://www.camresearch.net/showcitationlist.php?surname=Markowitz&initials=GS >,
> Z Yu<http://www.camresearch.net/showcitationlist.php?surname=Yu&initials=Z>,
> S Somlo<http://www.camresearch.net/showcitationlist.php?surname=Somlo&initials=S>,
> CM Crews<http://www.camresearch.net/showcitationlist.php?surname=Crews&initials=CM>
> *Departments of *Molecular, Cellular, and Developmental Biology, Internal
> Medicine, Genetics, Pharmacology, and Chemistry, Yale University, New Haven,
> CT 06511.*
>
> During kidney organogenesis, tubular epithelial cells proliferate until a
> functional tubule is formed as sensed by cilia bending in response to fluid
> flow. This flow-induced ciliary mechanosensation opens the calcium (Ca(2+))
> channel polycystin-2 (PC2), resulting in a calcium flux-mediated cell cycle
> arrest. Loss or mutation of either PC2 or its regulatory protein
> polycystin-1 (PC1) results in autosomal dominant polycystic kidney disease
> (ADPKD), characterized by cyst formation and growth and often leading to
> renal failure and death. Here we show that triptolide, the active diterpene
> in the traditional Chinese medicine Lei Gong Teng, induces Ca(2+) release by
> a PC2-dependent mechanism. Furthermore, in a murine model of ADPKD,
> triptolide arrests cellular proliferation and attenuates overall cyst
> formation by restoring Ca(2+) signaling in these cells. We anticipate that
> small molecule induction of PC2-dependent calcium release is likely to be a
> valid therapeutic strategy for ADPKD.
> [Pubmed Record - new window]<http://www.ionchannels.org/redirect.php?linkurl=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=RetrieveAMPERSANDdb=pubmedAMPERSAND dopt=AbstractAMPERSANDlist_uids=17360534AMPERSANDq uery_hl=2&readtype=medline&site=camresearch&pmid=1 7360534&doctype=abstract>
>
>
> On Wed, Aug 19, 2009 at 7:33 AM, rachel schreiber <rachelsr (AT) hotmail (DOT) com>wrote:
>
>>
>> look for a good homeopathgood luck
>>
>>
>>
>>
>> rachel schreiber RCHom
>> classical homeopathy
>> tel/fax 972-2-6428550
>> mobile 972-50-8433223
>>
>> The Center for Complementary Medicine
>> Shaare Zedek Medical Center - Jerusalem
>>
>>
>>
>>
>> > To: homeopathy (AT) homeolist (DOT) com
>> > From: homeolist (AT) otherhealth (DOT) com
>> > Date: Sun, 16 Aug 2009 04:16:41 +0100
>> > Subject: [H] PKD Polycystic Kidney Disease
>> >
>> >
>> > I am 35 and have Polycystic Kidney Disease, at this point I am mostly
>> > asymptomatic aside from the occasional dull pains. I do have cysts that
>> > have grown in size. I am looking for any recommendations in homeopathic
>> > medicine that might be able to keep me i pretty good shape. Is there
>> > anything that can shrink cysts? Any information or suggestions would be
>> > appreciated.
>> >
>> > Thank you,
>> > Malikha
>> >
>> >
>> > --
>> > malikha
>> > ------------------------------------------------------------------------
>> > malikha's Profile: http://www.otherhealth.com/members/malikha.html
>> > View this thread: PKD Polycystic Kidney Disease
>> >
>> >

Over the years i have used the following formula [with some slight
variations sometimes] for ovarian cysts [of sizes which were "suspicious"]
I took the formula [combined the remedies] from Dr.med Emil Rehm: Bewahrte
homoopatische Rezepte [german]
palladium/platina/conium/apis/bufo D30 twice per day for a month or longer
if necessary.
Th results were very encouraging and as far as i remember in all cases the
cysts decreased or disappeared , even in one case of a teratoma which
totally ? disappeared to my big supprise[ time allowing i would like to
collect all the details of the last "case"]
I did always also give at the same time: evening primrose oil,some 1 gram
per day.

On Wed, Aug 19, 2009 at 7:39 AM, harold jitschak bueno de mesquita <
bdmesq (AT) gmail (DOT) com> wrote:

>
> Triptolide is a traditional Chinese medicine-derived inhibitor of
> polycystic kidney disease.
>
> SJ Leuenroth<http://www.camresearch.net/showcitationlist.php?surname=Leuenroth&initials=SJ >,
> D Okuhara<http://www.camresearch.net/showcitationlist.php?surname=Okuhara&initials=D>,
> JD Shotwell<http://www.camresearch.net/showcitationlist.php?surname=Shotwell&initials=JD> ,
> GS Markowitz<http://www.camresearch.net/showcitationlist.php?surname=Markowitz&initials=GS >,
> Z Yu<http://www.camresearch.net/showcitationlist.php?surname=Yu&initials=Z>,
> S Somlo<http://www.camresearch.net/showcitationlist.php?surname=Somlo&initials=S>,
> CM Crews<http://www.camresearch.net/showcitationlist.php?surname=Crews&initials=CM>
> *Departments of *Molecular, Cellular, and Developmental Biology, Internal
> Medicine, Genetics, Pharmacology, and Chemistry, Yale University, New Haven,
> CT 06511.*
>
> During kidney organogenesis, tubular epithelial cells proliferate until a
> functional tubule is formed as sensed by cilia bending in response to fluid
> flow. This flow-induced ciliary mechanosensation opens the calcium (Ca(2+))
> channel polycystin-2 (PC2), resulting in a calcium flux-mediated cell cycle
> arrest. Loss or mutation of either PC2 or its regulatory protein
> polycystin-1 (PC1) results in autosomal dominant polycystic kidney disease
> (ADPKD), characterized by cyst formation and growth and often leading to
> renal failure and death. Here we show that triptolide, the active diterpene
> in the traditional Chinese medicine Lei Gong Teng, induces Ca(2+) release by
> a PC2-dependent mechanism. Furthermore, in a murine model of ADPKD,
> triptolide arrests cellular proliferation and attenuates overall cyst
> formation by restoring Ca(2+) signaling in these cells. We anticipate that
> small molecule induction of PC2-dependent calcium release is likely to be a
> valid therapeutic strategy for ADPKD.
> [Pubmed Record - new window]<http://www.ionchannels.org/redirect.php?linkurl=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=RetrieveAMPERSANDdb=pubmedAMPERSAND dopt=AbstractAMPERSANDlist_uids=17360534AMPERSANDq uery_hl=2&readtype=medline&site=camresearch&pmid=1 7360534&doctype=abstract>
>
>
> On Wed, Aug 19, 2009 at 7:33 AM, rachel schreiber <rachelsr (AT) hotmail (DOT) com>wrote:
>
>>
>> look for a good homeopathgood luck
>>
>>
>>
>>
>> rachel schreiber RCHom
>> classical homeopathy
>> tel/fax 972-2-6428550
>> mobile 972-50-8433223
>>
>> The Center for Complementary Medicine
>> Shaare Zedek Medical Center - Jerusalem
>>
>>
>>
>>
>> > To: homeopathy (AT) homeolist (DOT) com
>> > From: homeolist (AT) otherhealth (DOT) com
>> > Date: Sun, 16 Aug 2009 04:16:41 +0100
>> > Subject: [H] PKD Polycystic Kidney Disease
>> >
>> >
>> > I am 35 and have Polycystic Kidney Disease, at this point I am mostly
>> > asymptomatic aside from the occasional dull pains. I do have cysts that
>> > have grown in size. I am looking for any recommendations in homeopathic
>> > medicine that might be able to keep me i pretty good shape. Is there
>> > anything that can shrink cysts? Any information or suggestions would be
>> > appreciated.
>> >
>> > Thank you,
>> > Malikha
>> >
>> >
>> > --
>> > malikha
>> > ------------------------------------------------------------------------
>> > malikha's Profile: http://www.otherhealth.com/members/malikha.html
>> > View this thread: PKD Polycystic Kidney Disease
>> >
>> >

I am a fellow PKD patient and AFAIK triptolide has, in purely allopathic terms, shown some promise in the reduction of kidney cysts in the mouse model of PKD. I'm not at all sure that it can be regarded as "an inhibitor of PKD" as not only would we need to learn more about how this might work in humans over a long period of time (the disease often progresses very slowly over decades), we would also need to assess overall effects on this systemic disease (which can, and often does, include extra-renal effects such as cardiovascular problems, cerebral aneurysms, liver cysts and mitral valve prolapse). Even then, we might want to be concerned about the essentially suppressive or palliative nature of such a treatment.

I am also very uncertain about the use of combination remedies but I'm sure that the practising homeopaths on these boards will step in and give more advice on this subject. That said, I personally have experienced some quite severe or pronounced reactions to single remedies and I think it might be difficult to separate out and evaluate the effects of several remedies taken at once. It also smacks of the "this for that" approach gone mad - greater minds than mine have spoken about this on these boards so take a look.

Advice to "find a good homeopath" should, I think, be expanded on these boards, to include specific guidelines on how to choose very carefully to find a genuine homeopath. There is even disagreement here as to what constitutes homeopathy so I would urge caution. Sadly even registration with a professional organisation confers no guarantee (I've been given decidedly fluffy, New Agey advice from some members of the SoH and remedies which have shaken me to my very soul without offering any improvement or stabilisation of my PKD. Also, homeopaths who've described themselves as "classical" have nonetheless deemed it OK to continue taking other medications).

A checklist of what to look for, what to avoid, what to expect would be very helpful. Likewise some relevent case histories (C'mon homeopaths!) - if we're going to look at disease labels then treatments for polycystic ovaries probably won't be helpful in this case. PKD is very different, the individuals with these symptoms very different again - I see an extremely wide variation in those affected by ADPKD. Considering kidney health alone, some PKDers progress to renal failure very early in life, others never do. The deterioration isn't necessaily straight line either.

Please be careful & do some research before committing. Experimentation is not really a good idea with this disease!

I agree, I don't want to be my own guinea pig or anyone elses for that matter. I also don't want to go through what my mother has gone through. She is 65 and had a kidney transplant on 2001 (thankfully) after many a horrible hospital experience with kidney problems.But now has stage 4 cancer most likely as a result of the meds she had to take for her new kidney. She a fighter though and I have faith she will make it through this big bump in the road.

In your experience with pkd have you found anything that has been useful in homeopathic medicine?

There are not too many homeopaths in my area, but I will have to choose one so I will have a more directed approach to this whole thing. I'm still in the research phase.