Dear Fredric
But then Nature throws us for a loop by having people that show symptoms of the exact polar opposite.
Example you mentioned;
coffee with most gets people wired/loads of energy/can't sleep after drinking it. (stimulant)
Those that are polar opposite have 180 degree the flipside happening.
The human body is not as predictable as we might hope.
On another subject but somewhat related;
Within the practice of kinetic muscle testing the practicioner can reverse this polarity within minutes.