I wanted to know the reasons, has got nothing to do with interfering with the case.
So, to recap, there are 4 most probable reasons in case if a well chosen remedy doesn't work, as follows:
1. The remedy is being used up quickly and therefore needs repeating more frequently
2. The remedy is being antidoted (coffee, mints, maintaining conditions like stress)
3. A 10M or 50M should be tried. i.e. wrong potency
4. There is a miasmic block and an intercurrent nosode needs to be given after which the well indicated Rx should work.
Thanks to all especially Ricky, for putting it in a consolidated way, thanks again.
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