I have gotten aggravations at low potencies. Both followed by ameliioration and not. An aggravation is an increase in presenting symptoms, while a side effect is a new symptom that is part of the remedy picture. I've experienced that, too. But what I wanted to convey was that I have seen aggravations occur at all potencies, high & low. In low potencies, they merely last a shorter length of time. If there is an aggravation without an amelioration, I consider that the person is merely getting worse and it was the wrong remedy. The aggravation at a low potency is especially noticeable in acutes. I tend to not give lows constitutionally unless there is some specific reason why I'm not comfortable with the highs, e.g., someone on dialysis.

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Shirley Reischman