Hi Shirl,
A medicinal aggravation is when the person has symptoms of the remedy that he has not experienced before. A homeopathic aggravation is when his own symptoms become worse. There is also the curative 'peeling off the layers of the onion' response, where old symptoms return. A medicinal aggravation is a bad thing. The other two are relatively good signs that the remedy is correct, but we really don't want the person to suffer. If there is a homeopathic aggravation, we want it to be very mild and short lived. The ideal is no aggravation with amelioration. This is where picking the correct dose (quantity, dry or liquid, and potency) become so important.
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Shirley Reischman
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