hello karin, and other learned colleagues
organon paras 179 -184 are relevant to this situation as i understand it. notably para 181.

boenninghausen's concordances are a great help in selecting the remedy according to organon para 184, after the well-selected first remedy has done its work.

puls is not sensitive to weather changes which is a main modality here so i would think of changing remedies for this reason too. many remedies are sensitive to fats.

also you can ask yourself, according to hahnemann's list of psoric disease in Chronic Diseases, do i need to treat this as a psoric case, using primarily the antipsoric remedies? [low energy, needs reassurance, sensitive to weather give hints]

hans weitbrecht's method of giving lm's makes sense to me and an article can be found on www.boger-boenninghausen.com