Have been suffering cyclical bouts of acute depression for the past year. Diagnos is Bipolar Disorder, as best I can discern from my doctor's muttered pronouncements.

Emotional: feelings of withwrawal, "separateness" from daily life. Irritability toward loved ones, then going back with tearful apologies. Want the loved one(s) nearby, but to leave me alone. Feelings of dread for the future: environnmental crises, finances, etc.

Physical: food aversion at times; have dropped to 138 lb, am back up to 142, normal weight about 155 lb. Hypersomnia,insomnia. Dead tone in voice. Have run the full gamut of Rx drugs, from alprazolam to Zyprexa. History of treatment: each different med "seems to work well at first", for approx. 30-60 days, then drug's effectiveness wanes.

Mental: Thoughts of imminent environnmental catastrophe(flooding of coastal areas from ice-melt, increase in skin melanoma from ozone holes, destruction of rain forests, dying of coral reefs, etc.) Hopelessness,futility.

Peculiar Symptoms: periods of "normalcy" when I'm functional, able to work, even smile and make jokes. During these times, can go without sleep for 48-72 hours, after which I crash for an entire day. Symptoms are CYCLICAL.

Treatment Notes: Hypericum in standardized form ineffective. Have tried Sulphur 30C(I am a definite Sulphur Type, believe me) in the hope that it might work constitutionally. Seems to work for a couple days, then effect fades.
Have not tried continual doses of Sulphur 30C, which is the only potency I have.

Questions: Should I try a regimen of the Sulphur 30C for several days? Should I try a single high-potency dose(knowing for certain that I am a Suplhur Personality)?

TIA,
Neuly56