It is a challenge for me to treat this patient through homeopathy. I have also done herbal course. But I believe that homeopathy has lot of potential to treat this kind of patient.

Before sending this case to BB for mutual discussion and opinions. I referred the patient for renal biopsy. Today, I received this report. I was waiting for this report. I believe that it is a matter of health of a patient. So, I am going to write complete report with conclusion.

1. Report: The biopsy contains tissue from both cortex and medulla. It contains up to eight glomeruli per section. Two are obsolete. The rest of the glomeruli are all involved, but the degree of involvement varies somewhat. The basic lesion is a segmentally accentuated, measangial hypercellularity, which is associate with segmental mesangial widening. The widened mesangia sometimes stain intensely with eosin. Occasionally, small eosinophilic deposits can be identified in them. Focal fibrin exudation is seen in one glomerulus. Capsular adhesions are present in two glmeruli. No peripheral, segmental, proliferative lesions or crescents are present.

The tubulointerstitial parenchyma shows good preservation of the tubules in most of the biopsy, but streaky areas of interstitial fibrosis are present, mostly in relation to the obsolete golomeruli. The scars contain atrophic tubules and a mild, mononuclear, cellular infiltrate.

The vessels are not remarkable.

I.F. Report: The snap frozen tissue contains two glomeruli. They show positive, mesangial staining for IgA, C3, and lambda light chains. Staining for Rappa Light chains is milder. No fluorescent staining is present for IgG, IgM, C4 or fibrinogen.

Conluding Comments: Chronic Glomerulonephritis, ? IgA.

3. E.M. Report: The plastic embedded material contained no glomeruli. The paraffin embedded tissue was reprocessed for E.M. The basic glomerular structure was well preserved. Mild mesangial hypercellularity, mesangial widening and matrix increase were present. Small clumps of electron dense deposits were present along the periphery of the mesangial waists.

Diagnosis: Segmentally accentuated mesangial proliferative glomerulonephritis, with

Mesangial IgA deposits
Consistent with IgA associated nephropathy

Could any one help in accomplishing my challenge.