Hi, I didn't notice anything with first dose of Bryonia. After the 2nd dose I woke up 4 hours later (2:00 AM) and he had NO fever! His breathing sounded very good. Woke up (4:00 AM) his fever was back, 103 degrees. Another dose of Bryonia and Motrin. It's now 10:00AM and he has no fever and sounds very good. Still asleep. He drank water throughout the night. I will try today without Motrin and see how is fever is. If he gets hot again do I give another dose? or give a dose anyway when he wakes up? Thank You, Ens