My friend went back to California and got really bad, took the lM Ignatia, felt like she wanted to kill herself, called a suicide prevention clinic, made an appointment with a psychiatrist. Then she took the 50M Lachesis, and she felt better for a couple of days. She felt the beginning of the bad feelings coming back so about 5 days later she took another dose of the 50M. When she told me this I got really upset because I told her not to take a second dose of any of the remedies.Anyway, a week after that 2nd dose she called me and said she feels fine, working hard at her job and doesn't think about it at all. ??????? Beats me.Guess we'll have to see what happens in a couple of weeks from now.