Update: 48 hours after taking the Puls. 1M

He has had one migraine each night, about one hour after going to bed. Feeling like will get one pretty much all the time though. The nature of the pain does not seem any different.The migraine which started on the right side, switched once to the left (so he thought they were changing sides) has switched back to the right again. He states it feels like it wants to switch again. This makes the pain occur in the forehead and sinus' as well. The forehead and sinus pain while the pain tries to switch is typical he says.
First night after Puls had a very restless night's sleep. Was kicking the covers all over the place (he was dreaming he was playing soccer....he usually doesn't dream much) he woke up when he actually hit his shin very hard on the bunk wall of his truck cab.
Then last night, after getting his migraine ....he said he slept very well. He states no other symptoms other than what already described. He has been avoiding the potential antidotes as instructed.
What to do now?